{"id":578,"date":"2022-06-02T14:24:00","date_gmt":"2022-06-02T14:24:00","guid":{"rendered":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578"},"modified":"2023-11-03T14:28:06","modified_gmt":"2023-11-03T14:28:06","slug":"adrenergic-receptorsin-breast-cancer","status":"publish","type":"post","link":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578","title":{"rendered":"Adrenergic receptorsin breast cancer"},"content":{"rendered":"\n<p class=\"has-text-align-left\">Cecilia P\u00e9rez Pi\u00f1ero,\u00a0Ezequiel Mariano Rivero,\u00a0Luc\u00eda Gargiulo,\u00a0Mar\u00eda Sol Rodr\u00edguez,\u00a0Carlos David Bruque,\u00a0Ariana Bruzzone,\u00a0Isabel Alicia L\u00fcthy<sup>\u00a0<\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p>Breast cancer is the most diagnosed malignancy in women worldwide and in the majority of the countries. Breast cancers are classified on the expression of estrogen and progesterone receptor expression and overexpression of human epidermal growth factor receptor 2 (HER2) as luminal, HER2+ and triple negative breast cancer. The intrinsic molecular subtypes match this classification. Cancer diagnosis and treatment cause distress. In both acute and chronic stress, the secreted catecholamines adrenaline and noradrenaline trigger the \u00abfight-or-flight\u00bb response. This chapter focuses on the actions of the \u03b22 and \u03b12 adrenergic receptors in several models of breast cancer. The actions of these receptors depend on the model used to investigate them. The \u03b2<sub>2<\/sub>-adrenergic receptors seem to exert a dual action. They can directly act on the epithelial cells inhibiting cell proliferation and migration\/invasion and indirectly upon the immune microenvironment. The proportion of \u03b22 receptors in each compartment could, therefore, lean the scale to an inhibition or to an exacerbation of tumor growth, invasion and metastasis. All the work points to a beneficial or neutral action of \u03b2-blockers on breast cancer. With respect to \u03b12-adrenergic receptors, the investigation performed by our group suggest that the \u03b12B and the \u03b12C receptors are linked to enhanced cell proliferation and tumor growth acting through both the epithelial and the stromal (fibroblastic) compartments while \u03b12A could be beneficial for patients. Some adrenergic compounds could be repurposed for breast cancer treatment due to their very low side effects and very well-known pharmacology.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-100\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36357079\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ver Publicaci\u00f3n<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Cecilia P\u00e9rez Pi\u00f1ero,\u00a0Ezequiel Mariano Rivero,\u00a0Luc\u00eda Gargiulo,\u00a0Mar\u00eda Sol Rodr\u00edguez,\u00a0Carlos David Bruque,\u00a0Ariana Bruzzone,\u00a0Isabel Alicia L\u00fcthy\u00a0 Abstract Breast cancer is the most diagnosed malignancy in women worldwide and in the majority of the countries. Breast cancers are classified on the expression of estrogen and progesterone receptor expression and overexpression of human epidermal growth factor receptor 2 (HER2) as [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":521,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_uag_custom_page_level_css":"","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[11],"tags":[],"class_list":["post-578","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publicaciones"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Adrenergic receptorsin breast cancer - UCT HP<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adrenergic receptorsin breast cancer - UCT HP\" \/>\n<meta property=\"og:description\" content=\"Cecilia P\u00e9rez Pi\u00f1ero,\u00a0Ezequiel Mariano Rivero,\u00a0Luc\u00eda Gargiulo,\u00a0Mar\u00eda Sol Rodr\u00edguez,\u00a0Carlos David Bruque,\u00a0Ariana Bruzzone,\u00a0Isabel Alicia L\u00fcthy\u00a0 Abstract Breast cancer is the most diagnosed malignancy in women worldwide and in the majority of the countries. Breast cancers are classified on the expression of estrogen and progesterone receptor expression and overexpression of human epidermal growth factor receptor 2 (HER2) as [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\" \/>\n<meta property=\"og:site_name\" content=\"UCT HP\" \/>\n<meta property=\"article:published_time\" content=\"2022-06-02T14:24:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-03T14:28:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png\" \/>\n\t<meta property=\"og:image:width\" content=\"250\" \/>\n\t<meta property=\"og:image:height\" content=\"200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Mirtha\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mirtha\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#article\",\"isPartOf\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\"},\"author\":{\"name\":\"Mirtha\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/person\/cb3d81609139435146e1257936dc9b98\"},\"headline\":\"Adrenergic receptorsin breast cancer\",\"datePublished\":\"2022-06-02T14:24:00+00:00\",\"dateModified\":\"2023-11-03T14:28:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\"},\"wordCount\":274,\"publisher\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization\"},\"image\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png\",\"articleSection\":[\"publicaciones\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\",\"name\":\"Adrenergic receptorsin breast cancer - UCT HP\",\"isPartOf\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage\"},\"image\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png\",\"datePublished\":\"2022-06-02T14:24:00+00:00\",\"dateModified\":\"2023-11-03T14:28:06+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png\",\"contentUrl\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png\",\"width\":250,\"height\":200,\"caption\":\"elsevier\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Adrenergic receptorsin breast cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#website\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/\",\"name\":\"UCT HP\",\"description\":\"Unidad de Conocimiento Traslacional Hospitalaria Patag\u00f3nica\",\"publisher\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization\"},\"alternateName\":\"Unidad de Conocimiento Traslacional Hospitalaria Patag\u00f3nica\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization\",\"name\":\"UNIDAD DE CONOCIMIENTO TRASLACIONAL HOSPITALARIA PATAG\u00d3NICA\",\"alternateName\":\"UCTHP\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/logo-UCT-HP.png\",\"contentUrl\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/logo-UCT-HP.png\",\"width\":1191,\"height\":357,\"caption\":\"UNIDAD DE CONOCIMIENTO TRASLACIONAL HOSPITALARIA PATAG\u00d3NICA\"},\"image\":{\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/person\/cb3d81609139435146e1257936dc9b98\",\"name\":\"Mirtha\",\"url\":\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?author=2\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Adrenergic receptorsin breast cancer - UCT HP","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578","og_locale":"es_ES","og_type":"article","og_title":"Adrenergic receptorsin breast cancer - UCT HP","og_description":"Cecilia P\u00e9rez Pi\u00f1ero,\u00a0Ezequiel Mariano Rivero,\u00a0Luc\u00eda Gargiulo,\u00a0Mar\u00eda Sol Rodr\u00edguez,\u00a0Carlos David Bruque,\u00a0Ariana Bruzzone,\u00a0Isabel Alicia L\u00fcthy\u00a0 Abstract Breast cancer is the most diagnosed malignancy in women worldwide and in the majority of the countries. Breast cancers are classified on the expression of estrogen and progesterone receptor expression and overexpression of human epidermal growth factor receptor 2 (HER2) as [&hellip;]","og_url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578","og_site_name":"UCT HP","article_published_time":"2022-06-02T14:24:00+00:00","article_modified_time":"2023-11-03T14:28:06+00:00","og_image":[{"width":250,"height":200,"url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","type":"image\/png"}],"author":"Mirtha","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Mirtha","Tiempo de lectura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#article","isPartOf":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578"},"author":{"name":"Mirtha","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/person\/cb3d81609139435146e1257936dc9b98"},"headline":"Adrenergic receptorsin breast cancer","datePublished":"2022-06-02T14:24:00+00:00","dateModified":"2023-11-03T14:28:06+00:00","mainEntityOfPage":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578"},"wordCount":274,"publisher":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization"},"image":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage"},"thumbnailUrl":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","articleSection":["publicaciones"],"inLanguage":"es"},{"@type":"WebPage","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578","name":"Adrenergic receptorsin breast cancer - UCT HP","isPartOf":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage"},"image":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage"},"thumbnailUrl":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","datePublished":"2022-06-02T14:24:00+00:00","dateModified":"2023-11-03T14:28:06+00:00","breadcrumb":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#primaryimage","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","contentUrl":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","width":250,"height":200,"caption":"elsevier"},{"@type":"BreadcrumbList","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?p=578#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/"},{"@type":"ListItem","position":2,"name":"Adrenergic receptorsin breast cancer"}]},{"@type":"WebSite","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#website","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/","name":"UCT HP","description":"Unidad de Conocimiento Traslacional Hospitalaria Patag\u00f3nica","publisher":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization"},"alternateName":"Unidad de Conocimiento Traslacional Hospitalaria Patag\u00f3nica","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#organization","name":"UNIDAD DE CONOCIMIENTO TRASLACIONAL HOSPITALARIA PATAG\u00d3NICA","alternateName":"UCTHP","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/logo\/image\/","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/logo-UCT-HP.png","contentUrl":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/logo-UCT-HP.png","width":1191,"height":357,"caption":"UNIDAD DE CONOCIMIENTO TRASLACIONAL HOSPITALARIA PATAG\u00d3NICA"},"image":{"@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/#\/schema\/person\/cb3d81609139435146e1257936dc9b98","name":"Mirtha","url":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?author=2"}]}},"author_meta":{"display_name":"Mirtha","author_link":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?author=2"},"featured_img":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png","uagb_featured_image_src":{"full":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false],"thumbnail":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier-150x150.png",150,150,true],"medium":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false],"medium_large":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false],"large":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false],"1536x1536":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false],"2048x2048":["https:\/\/ucthp.hospitalelcalafate.gob.ar\/wp-content\/uploads\/2023\/10\/elsevier.png",250,200,false]},"uagb_author_info":{"display_name":"Mirtha","author_link":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?author=2"},"uagb_comment_info":0,"uagb_excerpt":"Cecilia P\u00e9rez Pi\u00f1ero,\u00a0Ezequiel Mariano Rivero,\u00a0Luc\u00eda Gargiulo,\u00a0Mar\u00eda Sol Rodr\u00edguez,\u00a0Carlos David Bruque,\u00a0Ariana Bruzzone,\u00a0Isabel Alicia L\u00fcthy\u00a0 Abstract Breast cancer is the most diagnosed malignancy in women worldwide and in the majority of the countries. Breast cancers are classified on the expression of estrogen and progesterone receptor expression and overexpression of human epidermal growth factor receptor 2 (HER2) as&hellip;","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/ucthp.hospitalelcalafate.gob.ar\/?cat=11\" class=\"advgb-post-tax-term\">publicaciones<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">publicaciones<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Publicado 4 a\u00f1os hace","modified":"Actualizado 3 a\u00f1os hace"},"absolute_dates":{"created":"Publicado el 2 de junio de 2022","modified":"Actualizado el 3 de noviembre de 2023"},"absolute_dates_time":{"created":"Publicado el 2 de junio de 2022 2:24 pm","modified":"Actualizado el 3 de noviembre de 2023 2:28 pm"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/posts\/578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=578"}],"version-history":[{"count":2,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/posts\/578\/revisions"}],"predecessor-version":[{"id":580,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/posts\/578\/revisions\/580"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=\/wp\/v2\/media\/521"}],"wp:attachment":[{"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=578"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=578"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ucthp.hospitalelcalafate.gob.ar\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}